CHAPTER 7: EXAMINING THE PATIENT
 
 
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Objectives

After studying this chapter, you should be able to:

  1. Examine a patient for symptoms and signs of poisoning.
  2. Describe the patient's condition to a doctor over the telephone or in writing.
  3. Decide whether a patient is seriously ill.
  4. Recognize common poisoning syndromes.

If you are more than two hours journey from a hospital and there is no doctor or health centre nearby, your next step, after giving first aid, should be to examine the patient.

It is important to examine the patient so that you can decide how to help the patient until he or she gets to hospital and so that you can give a clear account of the patient's condition if you contact a poisons centre or hospital by telephone or radio.

This chapter describes how someone without medical training can examine a patient for the effects of poisoning. Reading it can help you learn what to do and what to look for, but it is best if a trained health care worker shows you how to carry out an examination. Practise counting the pulse and reading a thermometer until you are confident you can do both accurately.

Poisons may cause many changes inside the body that can only be measured using medical equipment. Such changes are not discussed here.

Symptoms and signs

The effects of poisoning are known as symptoms and signs.

Symptoms are effects that the person feels or senses, for example, pain, nausea, or thirst. To find out what symptoms the patient has, ask the patient these questions: "How do you feel?" "What do you feel?"

Signs are effects that you can see, feel, hear or measure, for example, vomiting, fever, a fast pulse, noisy breathing and unconsciousness.

Most poisons cause several symptoms and signs because they affect more than one part of the body.

For each of the signs described in this chapter there is a box with a list of some of the common chemicals that cause it. To keep the lists short, some of the names are those of groups of chemicals (for example: atropine-like medicines) rather than the names of individual chemicals. The names used here are also used in Part 2, so you can check in Part 2 to see which individual chemicals are included in a group. The lists do not include every chemical that causes a particular effect, so it is possible that a person with one of the signs or symptoms could have been poisoned by a chemical that is not listed.

Do not expect a patient to have all the signs and symptoms listed for a poison. Often it depends how badly poisoned the patient is. For example, ethanol (alcohol) can cause unconsciousness, but someone
poisoned with ethanol may not be unconscious. He or she may simply be drunk and be unsteady and talkative.

Remember, the patient may have taken more than one poison.

What the examination cannot tell you

If you have no clue about what the poison might be, the examination is unlikely to give you information that will point to one particular poison, because many poisons cause similar symptoms and signs. However if you already think you know what the poison might be, and what happened, you can check whether you might be right by comparing the patient's symptoms and signs with those listed for specific poisons in Part 2 of this book.

You may not be able to tell, just by examining the patient, if the patient is poisoned or if he or she is suffering from another illness or injury, because:

  • many poisons cause symptoms and signs that are similar to the symptoms and signs of diseases or injuries;
  • sometimes a patient may be poisoned and suffering from the effects of another illness or injury.

For this reason, when you examine the patient it is important to ask if he or she has now, or used to have, any sickness or disease, and to look for cuts and bruises and other signs of injury.

When the patient does not have any symptoms or signs

A patient who seems well may not have been poisoned. Remember, exposure to poison will not result in poisoning if a poisonous dose does not get into the body (see Chapter 1).

Someone who has been poisoned may seem well because it is too soon for the poison to take effect. Some poisons may not cause any effects for many hours. For example, a person who takes a poisonous dose of paracetamol may be well for up to 48 hours afterwards. So it is important to ask what happened and how long ago.

How to examine a patient and find out the symptoms and signs

Carry out the examination in the order given in this chapter. As you examine the patient, write down all your findings with a note of the date and time. At regular intervals while you are looking after the patient, check how he or she is and write down any changes in signs and symptoms and the time when you notice them. Give your report to the doctor when you hand over the patient.

Talk to the patient

If the patient is conscious and can answer questions talk to the patient.

Ask what happened

Try to find out:

  • what the poison is;
  • whether the poison was swallowed, breathed in, injected, or in contact with the skin or the eye, or whether the patient was bitten or stung;
  • how long ago the patient was poisoned. Did it happen a few minutes ago, or was it several hours or even days ago?
  • how long the patient was exposed; for example, if the patient breathed in poison, for how long was it breathed in, or if the poison was spilt on the skin or clothes, how long was it before the patient washed or took off the clothes.
  • if the patient feels sick, how long he or she has been feeling like this.

Ask the patient if he or she has had a fall or injury. Ask if the patient knows anybody else in the family, in the village or at work who has had the same sickness.

Sometimes the patient can tell you what happened. For example, people usually know if they have been bitten or stung by an animal and they will often tell you when they have taken an overdose of medicine. They may tell you that a chemical product or a pesticide they were using has made them ill.

In some circumstances people do not know what happened. For example, people who have been poisoned by carbon monoxide gas may not know what has made them feel sick, because carbon monoxide has no smell and is invisible. People who are sick after using a chemical product or pesticide may not realize that their sickness is due to poisoning.

Even when people know what happened they may not be able to tell you much about the poison. People often use chemicals or take medicines without knowing what they contain. Even if they give you the bottle, there may not be any information on the label about the contents. People who have been bitten by a snake may not know what kind of snake it was, and may not be able to give a good enough description for anyone else to identify it. Sometimes people who think they know about wild plants and mushrooms make mistakes in identification.

Sometimes people do not know how much poison they have taken. People who take poison because they want to harm themselves may not count how many tablets they take, or measure how much liquid they drink.

Some people may not want to tell you the truth and may lie about what they have taken. A child may be too frightened to tell the truth.

The patient may be dazed, in shock or confused and not able to answer properly. People who are unconscious cannot tell you anything, and children may be too young to talk or to understand.

Later, you may be able to find out more about what happened by asking other people and looking for evidence (see Chapter 8), but examine the patient first.

Ask the patient about symptoms

Ask if the patient feels pain. Ask where the pain is. Ask whether the patient feels cold, hot, thirsty, weak, sick, dizzy, or faint. Ask how long the patient has felt like this. Ask whether the patient has been unconscious or asleep.

A patient who is confused:

  • may be agitated and frightened;
  • may not be able to remember what day it is, what time of year it is, or where he or she is;
  • may not be able to think properly or to remember things;
  • may have hallucinations, which means seeing things that are not real, or feeling things like ants crawling on the skin.

Some chemicals that may cause confusion or hallucinations

Medicines: aminophylline, amitriptyline and other tricyclic antidepressants, antihistamines, atropine-like medicines, dapsone, ephedrine, insulin, propranolol and other ß-blockers, pseudoephedrine .

Drugs of abuse: amfetamines, cannabis, cocaine.

Pesticides: chlorophenoxyacetate weedkillers, organophosphorus and carbamate pesticides.

Other chemicals: camphor, camphorated oil, ethanol, turpentine and other volatile oils.


The patient may not be able to hear you. A person poisoned by aspirin or quinine may hear a ringing sound in the ears, or may become deaf.

Look for signs of poisoning

This section describes how to examine a patient for some common signs of poisoning:

  • unconsciousness,
  • changes in the skin, breathing, pulse, temperature, eyes, or behaviour,
  • vomiting and diarrhoea,
  • dehydration,
  • not passing urine,
  • fits,
  • signs of liver damage.

Watch the way the patient behaves

Some poisons make the patient restless, overactive, or aggressive. This can also happen when people suddenly stop abusing drugs or drinking alcohol after doing so for a long time.


Some chemicals that may cause overactivity, restlessness or irritability

Medicines: aminophylline, atropine-like medicines, chlorpromazine and other phenothiazines, ephedrine.

Drugs of abuse: amfetamines, cocaine.


Strange behaviour may be a sign that the patient abuses drugs or other substances, or it may be a sign of mental illness.

The unconscious patient

A person who is losing consciousness may seem very drowsy, may only be able to say yes or no if you ask questions, or may only be able to obey commands such as "open your eyes" or "lift up your arm".
The patient may soon become unconscious.

Unconsciousness is a sign of dangerous illness. Put an unconscious patient in the recovery position so that the tongue does not block the airway.

Try to find out whether the patient became unconscious suddenly or gradually became drowsy and fell asleep. Most poisons cause gradual unconsciousness if they have been swallowed.


Some chemicals that may cause unconsciousness

Medicines: amitriptyline and other tricyclic antidepressants, antihistamines, atropine-like medicines, barbiturates, carbamazepine, chloroquine, chlorpromazine and other phenothiazines, chlorpropamide-like medicines, diazepam and other benzodiazepines, insulin, iron-containing medicines, meprobamate,
quinidine, quinine, sodium valproate.

Other chemicals: benzene, carbon monoxide, carbon tetrachloride, cyanide, ethanol, ethylene glycol, methanol, toluene, trichloroethane, trichloroethylene, xylene.

Many other medicines and chemicals taken in large amounts.


Other common causes of unconsciousness are head injury, fainting, heavy bleeding, heart attack, stroke, lack of air, epilepsy, fits, and diabetes.

Unconsciousness is probably caused by a head injury if the patient also has any of these signs:

Look at the patient

Does the patient look ill or weak? Look at the patient's clothes to see if they are damp or stained with chemicals, urine or vomit. Look at the vomit to see whether there is blood, or pieces of tablets, plants, or food in it.

Look at the skin

Cuts, scratches, bruises, or bleeding may mean the patient is ill because of an injury.

Bruises may be caused by a fall. The patient may have been dizzy, unsteady, or very drowsy because of alcohol or drugs.

Cuts on the insides of the wrists or on the neck may have been made by the patient trying to kill himself or herself, and scar lines could mean that the patient tried to do this in the past.

Marks on the arms near the inside of the elbow, or on the ankles or knees, with swollen veins, ulcers and abscesses may have been caused by injecting drugs. The patient may be dependent on drugs.

Burns and stains may have been caused by corrosive or irritant liquids. Someone who has been working with a chemical may have burns on the legs, arms, chest, back, or feet. Someone who has swallowed a
corrosive substance may have burns and stains on the chin and lips, and on the chest if liquid spilt out of a bottle.

Blisters or red patches on the sides of fingers, ankles, knees, shoulders, or other parts of the body show that the patient has been lying unconscious in the same position for several hours.

Scaly rashes may be caused by working with irritant chemicals, such as pesticides, or handling irritant plants. Rashes are also caused by some diseases and parasites.

A hot pink skin may be caused by some medicines. If the patient has a black or brown skin, feel the skin and look at the hands and inside the lips.

A blue colour to the skin and inside the eyelids and lips means that there is not enough oxygen in the blood. Usually this means that the patient cannot breathe properly, but some chemicals make the patient look blue even though breathing is good. If the patient has a brown or black skin it may be difficult to see a blue colour to the skin, but the lips, nails and inside of the lower eyelids will look
blue and the skin will lose its shine. Blue-coloured skin is a sign of dangerous illness.

A yellow skin may be caused by jaundice or by chemicals that stain the skin. Jaundice is caused by liver damage. The liver damage may be due to poisoning or infection, or damage to the blood. The whites of the eyes will also be yellow. It can take up to 48 hours after poisoning before the skin turns yellow.

Some yellow or orange substances turn the skin yellow or orange. The medicine called rifampicin gives an orange-red colour to the skin (the stain washes off), urine, stools, tears, and whites of the eyes.


Some chemicals that may make the skin change colour

Pink, hot skin: atropine-like medicines, amfetamines, and borax.

Yellow skin caused by jaundice: carbon tetrachloride, iron containing medicines, paracetamol, pentachlorophenol, trichloroethylene, and some poisonous mushrooms.

Yellow or orange stain: dinitrophenol, dinoseb, DNOC, rifampicin (the stain washes off).

Blue skin: dapsone, naphthalene, paradichlorobenzene, phenol, sodium chlorate, sodium nitrite.


Feel the skin

Poisons may cause sweating. Other causes of sweating are infection, shock, heart attack, and low blood sugar in diabetic patients.

Some substances cause hot dry skin. A hot dry skin may also be caused by being in a very hot place, or by sickness that causes fever.

Look inside the mouth

  • Burns and stains inside the mouth and throat show the patient has swallowed a corrosive or coloured substance.
  • Pieces of tablets in the mouth show the patient has swallowed tablets.
  • A coloured tongue may be caused by coloured tablets, berries or liquids.
  • Pieces of leaves or berries in the mouth show the patient has eaten a plant that may be poisonous.

Smell the breath

Many substances make the breath smell, even if only a small amount is swallowed. People may smell of alcohol but not be drunk. People often take alcohol when they take other poisons. If the patient smells of alcohol, look for evidence and signs of other poisons too. Look for evidence of head injury too.


Some chemicals that may make breath smell

Camphor, camphorated oil, carbon tetrachloride, cyanide, ethanol, methyl salicylate, paraffin, petrol, toluene, trichloroethylene, turpentine and other volatile oils, and many pesticides.


Watch and listen to breathing

  • Is the patient breathing more or less deeply than usual?
  • Is breathing more noisy than usual?
  • Is breathing difficult?

Count how many times the patient breathes in one minute. If the patient sees what you are doing he or she may breathe faster, so a good plan is to count breathing after taking the pulse, while you are still holding the wrist. Always count for a full minute.

Most adults breathe 12-18 times per minute, children and infants breathe 20-30 times per minute. People breathe more quickly when they are taking exercise or when they are excited or upset; they breathe more slowly when they are asleep or resting.

In most cases changes in breathing are dangerous and the patient's life may be in danger.

Slow and irregular breathing or fast and shallow breathing may be caused by poisoning, substances like vomit or kerosene getting into the lungs, unconsciousness, head injury, stroke, lung oedema (see below), lung infection, asthma, or diabetes.

Noisy breathing, with gurgling or snoring noises, may mean that the throat is blocked and not enough air is getting through. The throat may be blocked by food or a foreign body. If the throat is burnt it swells and blocks the airway. In an unconscious patient the throat may be blocked by the tongue, vomit or saliva if the patient is not in the recovery position.

Coughing or wheezing may be caused by irritant gases, smoke, or dust. The patient may also have stinging or severe pain in the eyes and nose. Kerosene and similar liquids cause coughing and choking if they are swallowed. Other causes of coughing and wheezing are infections of the lungs, asthma and cigarette smoking.


Same chemicals that may change breathing

Shallow breathing

  • Medicines: amitriptyline and other tricyclic antidepressants, antihistamines, atropine-like medicines, barbiturates, diazepam and other benzodiazepines, meprobamate, chlorpromazine and other phenothiazines.
  • Pesticides: carbamate and organophosphorus insecticides.
  • Other chemicals: carbon monoxide, ethanol.

Slow or irregular breathing

  • Medicines: opiates.
  • Pesticides: carbamate and organophosphorus insecticides.

Fast breathing

  • Medicines: aminophylline, aspirin and other salicylates, cocaine, chloroquine.
  • Pesticides: dinoseb, DNOC, organochlorine pesticides, pentachlorophenol.
  • Other chemicals: carbon monoxide (at first), ethanol, ethylene glycol, methanol, phenol.

Lung oedema

Lung oedema is a condition in which fluid fills the lungs and eventually stops the patient breathing. Lung oedema is a very serious condition and the patient's life may be in danger. The signs of lung oedema are:

  • fast breathing (20-40 times per minute), which is often noisy;
  • coughing with frothy spit so that the patient foams at the mouth and makes a gurgling noise in the throat;
  • grey or blue skin colour;
  • fast pulse;
  • sweating;
  • anxiety and fear;
  • crackling noises in the lungs, if you listen with a stethoscope or put your ear to the patient's chest;
  • difficulty in lying flat.

Some poisons cause lung oedema after a few minutes, others after several hours. As the patient gets tired, breathing may become very slow and may eventually stop.

The lungs may fill with fluid in conditions such as heart disease, but it happens in a different way.


Some chemicals that may cause lung oedema

  • Medicines: aspirin and other salicylates, chlorpromazine and other phenothiazines, opiates.
  • Pesticides: carbamate and organophosphorus insecticides, dinoseb, DNOC, paraquat, pentachlorophenol.
  • Other chemicals: ethylene glycol, petroleum distillates, turpentine and other volatile oils, irritant gases.

Check the pulse

The heart is a pump. It pushes blood through the blood vessels. Each time the pump pushes out blood a wave of pressure passes along the blood vessels. This is the heartbeat or pulse. It can be felt wherever the blood vessels are close to the surface of the body, by pressing the blood vessel gently against a bone.

Have a watch with a second hand in front of you. To take the pulse at the wrist, press two fingertips of your right hand lightly on the patient's wrist on the same side as the thumb (Fig. 38). You should feel a regular beat; this is the pulse. Count for a full minute looking at your watch. The number of beats you count in one minute is the pulse rate.

Fig. 38. Taking the pulse at the wrist.

In children and babies, try to find the pulse on the inside of the upper arm between the elbow and the shoulder. With your thumb on the outside of the child's arm, press your first and middle fingers gently into the groove between the muscles, until you feel a pulse. Sometimes it is easier to feel the heartbeat directly on the left of the chest.

A normal pulse is regular and strong. In an adult the pulse rate is between 60 and 80 per minute. In healthy young adults it may be slower (50-60 per minute). In young babies it is faster (120 per minute). The pulse rate is slower than normal during sleep, and faster than normal if the person is excited or moving about, so take the pulse when the person is resting.

Note if the pulse is:

  • fast or slow;
  • strong or weak, or with some beats stronger than others;
  • regular, with the same time between each beat, or irregular, with missed beats so that you cannot tap your foot in time to it.

If the pulse is very irregular when you feel it at the wrist, count the heartbeat by listening over the heart. You can hear the heartbeat if you put your ear against the nipple on the left side of the chest. The count may be higher this time because you will be able to hear heartbeats that were too weak to be felt at the wrist.

Write down what you find.

A change in the pulse can mean that the patient is dangerously ill.

Poisons may cause a slow pulse or a fast pulse. Any very bad poisoning may affect the heart, so that the pulse becomes irregular or very slow and may even stop altogether.


Some chemicals that may cause a slow pulse

  • Medicines: barbiturates, digitalis, digitoxin, digoxin, meprobamate, opiates, propranolol and other ß-blockers.
  • Pesticides: carbamate and organophosphorus insecticides.

A fast, weak pulse can mean shock, bleeding, heart attack, heat exhaustion or fever.

A fast, strong pulse can mean heat stroke, stroke, or heart disease.


Some chemicals that may cause fast pulse

  • Medicines: aminophylline, amitriptyline and other tricyclic antidepressants, antihistamines, aspirin and other salicylates, atropine-like medicines, ephedrine, isocarboxazid and other monoamine oxidase inhibitors, pseudoephedrine.
  • Drugs of abuse: amfetamines, cannabis, cocaine.
  • Pesticides: arsenic, chlorophenoxyacetate weedkillers, dinoseb, DNOC, pentachlorophenol.
  • Other chemicals: carbon monoxide (at first).

A slow pulse may be caused by a low body temperature.

Measure body temperature

It is wise to take a patient's temperature, even if there does not seem to be a fever. If the patient is very sick, take the temperature every 3 or 4 hours.

If you do not have a thermometer, feel the temperature by placing the back of one hand on the patient's forehead and your other hand on your own forehead. The forehead of a patient with a fever will feel warmer than yours. If the forehead feels cooler than yours the patient may have a low body temperature.

A thermometer can be used to measure temperature in the mouth, armpit, groin or rectum. You should not use the same thermometer in the rectum as you use for taking oral or armpit temperatures. Always use a thermometer with a round end for taking the temperature in the rectum as this will not damage the rectum.

To measure temperature:

  • Make sure that the column of mercury inside the thermometer is below about 35°C. If it is not, shake the thermometer until the level has gone down.
  • If the patient is awake, put the bulb of the thermometer in the mouth, under the tongue, for 2 minutes.
  • If the patient is drunk, agitated, confused or likely to have a fit, and might bite the thermometer, put it in the armpit, and place the arm firmly across the chest, for 5-10 minutes.
  • If the patient is unconscious, use a thermometer for taking temperature in the rectum. Push it gently into the rectum for a distance of 5 cm, and leave for 2 minutes before reading it.
  • If the patient is a child, take the temperature in the armpit, groin or rectum.

A normal body temperature is usually 36-37°C. The temperature in the mouth is 37.5°C. The temperature in the groin or under the arm is 0.5°C lower, and the temperature in the rectum is 0.5°C higher.

If the temperature is above 37.5°C the patient has a fever; the higher the temperature, the greater the fever. A temperature higher than 39°C is a sign of dangerous illness. Fever may be caused by infection or illness such as malaria. Only a few poisons cause fever.


Some substances that may cause a high body temperature and warm dry skin

  • Medicines: atropine-like medicines, antihistamines (more commonly in children than adults).
  • Plants: plants containing atropine.


Some chemicals that may cause a high body temperature and sweating

  • Medicines: aspirin and other salicylates (more commonly in children than adults), ephedrine, colchicine, isocarboxazid and other monoamine oxidase inhibitors, pseudoephedrine.
  • Drugs of abuse: amfetamines, cocaine.
  • Pesticides: dinoseb, DNOC, pentachlorophenol.
  • Other chemicals: naphthalene, phenol.

A low body temperature may be caused by a long period of unconsciousness, especially if the patient has been lying in an open or cold place.


Some chemicals that may cause a low body temperature (less than 35°C)

  • Medicines: amitriptyline and other tricyclic antidepressants, barbiturates, chlorpromazine and other phenothiazines, meprobamate, opiates.
  • Other chemicals: carbon monoxide, ethanol.

Look at the eyes

Examine both the patient's eyes together. See if the pupils are the same size.

Cover one eye at a time with your hand and see if the pupil changes size when the light changes. If you have a light you can shine it into the eyes and see if the pupils get smaller.

Unequal pupils-pupils that are not the same size-may be caused by a chemical splashed in one eye. If there has not been chemical in the eye, this is usually a sign of eye disease or brain disease.

Large pupils may be a sign of poisoning, or of severe lack of oxygen, or of very low body temperature.

Look at the whites of the eyes. If these are yellow this usually means the patient has jaundice.


Some chemicals that may affect the eyes

Very small "pinpoint" pupils

  • Medicines: opiates.
  • Pesticides: organophosphorus and carbamate insecticides.

Large pupils

  • Medicines: amitriptyline and other tricyclic antidepressants, antihistamines, atropine-like medicines, carbamazepine, ephedrine, isocarboxazid and other monoamine oxidase inhibitors, quinine.
  • Drugs of abuse: amfetamines.
  • Other chemicals: methanol.


Blurred vision

Loss of sight or complete blindness

  • Medicines: chloroquine, quinine.
  • Other chemical: methanol.

Other signs of poisoning

Vomiting and diarrhoea may be caused by almost any poison. Other causes of vomiting with diarrhoea are infections caused by bacteria, viruses, or worms, and malaria. Other causes of diarrhoea are allergies to certain foods, side-effects from certain medicines, such as antibiotics or laxatives, or eating too much unripe fruit or heavy, greasy foods. Other causes of vomiting are appendicitis or something blocking the gut, or almost any other sickness with high fever or severe pain, especially migraine headache, and infections of the liver, ears, and brain.

Black stools. The black colour may be caused by blood from the gut if the gut has been damaged by corrosive fluids. Iron tablets may colour stools black or dark green, and activated charcoal also colours
them black.

Dehydration. Vomiting and diarrhoea may lead to dehydration. A person with vomiting or diarrhoea loses a lot of water from the body. If he or she does not drink enough to replace the lost water, the body dries out. People of any age can become dehydrated, but dehydration develops more quickly and is most dangerous in small children. People with burns, or people who are unconscious and unable to drink, may also become dehydrated.

Signs of dehydration are as follows:

Very severe dehydration may cause a rapid weak pulse, fast deep breathing, fever, or fits.

The patient does not pass urine. If a person does not pass urine this could mean any of the following:


Some chemicals that may cause kidney failure

  • Medicines: aspirin and other salicylates, colchicine, iron containing medicines, isocarboxazid and other monoamine oxidase inhibitors, quinine, rifampicin.
  • Pesticides: arsenic, dinoseb, dinitrophenol, DNOC, paraquat, pentachlorophenol, sodium chlorate, thallium.
  • Other chemicals: boric acid, camphor, camphorated oil, carbon tetrachloride, ethylene glycol, methanol, naphthalene, phenol, sodium perborate, turpentine and other volatile oils.

The kidneys are making urine but the bladder is not working; the bladder muscles will not relax and let the urine out. Do not confuse this reason for not passing urine with kidney damage. If the bladder is full you should be able to feel a rounded swelling in the lower part of the belly. Some medicines stop people
emptying the bladder. This may also happen when a person has been unconscious a long time.


Some medicines that may stop the patient emptying his or her bladder

Amitriptyline and other tricyclic antidepressants, antihistamines, atropine-like medicines.


Fits (convulsions). These are jerking movements that the patient cannot control. The patient may be just twitching or the whole body may move. The patient may suddenly become unconscious and foam at the mouth. The longer the fit lasts, the greater the danger to life. In severe cases, the patient does not stop having fits and finds it difficult to breathe.

There are some kinds of fit where first the jaw and then the whole body becomes very stiff. This may be tetanus.

Fits may be caused by poisoning, lack of oxygen - which may be a result of exposure to poison or of something blocking the airway - epilepsy, meningitis, malaria, or low blood sugar in a diabetic person. People dependent on alcohol or drugs may have fits if they suddenly stop taking them.

In small children, fits may be caused by high fever or severedehydration.


Some chemicals that may cause fits

  • Medicines: aminophylline, amitriptyline and other tricyclic antidepressants, antihistamines, aspirin and other salicylates, atropine-like medicines, chloroquine, colchicine, dapsone, ephedrine, insulin and other antidiabetic drugs, iron salts, isocarboxazid and other monoamine oxidase inhibitors, opiates, phenothiazines, propranolol and other ß-blockers, pseudoephedrine, quinidine, quinine.
  • Drugs of abuse: amfetamine, cocaine.
  • Pesticides: arsenic, carbamate and organophosphorus insecticides, metaldehyde, sodium chlorate, strychnine, thallium.
  • Other chemicals: borax, boric acid, camphor, camphorated oil, carbon monoxide, cationic detergents, ethylene glycol, methanol, sodium perborate.

Signs of liver damage. The liver is the place where the body changes many poisons into less harmful substances. If there is more poison than the liver can deal with, the poison that does not get changed may damage the liver. The symptoms and signs of liver damage, which do not show for 2 or 3 days after poisoning, are as follows.


Some chemicals that may cause liver damage

  • Medicines: iron-containing medicines, paracetamol, rifampicin.
  • Pesticides: aluminium phosphide and zinc phosphide, pentachlorophenol,
  • Other substances: benzene, camphor, camphorated oil, carbon tetrachloride, phenol, tetrachloroethane, toluene, trichloroethane, trichloroethylene, xylene.

Poisonous mushrooms

Signs that the patient is severely ill

  • The patient is not breathing.
  • Breathing is wheezy or noisy after you have cleaned the mouth and put the patient in the recovery position.
  • The patient is unconscious and does not wake up when you pinch the hand.
  • The pupils do not change size when you shine a light into them.
  • The pulse is very slow (less than 50 beats per minute), or very fast (more than 110 beats per minute), or irregular, or very weak.
  • The patient has continuous fits.
  • The temperature in the mouth or rectum is over 39°C, or temperature under the arm or in the groin is more than 38°C.
  • The patient has severe belly pain.
  • There are signs of kidney failure.
  • There are signs of liver damage.

Patterns of symptoms and signs

Some poisons cause patterns of symptoms and signs that could not be caused by anything else. These patterns are often called poisoning syndromes. The chemicals and medicines that cause some common
poisoning syndromes are listed in Table 7.1.

Table 7.1. Poisoning syndromes

Poisons

Symptoms and signs

Atropine, amitriptyline, antihistamines, Datura stramonium, Atropa belladonna, some kinds of mushrooms dry, hot skin, fever, thirst, dry mouth, large pupils, fast pulse, difficulty in passing urine, hallucinations, fits, shallow breathing, unconsciousness
Organophosphorus and carbamate insecticides, some kinds of mushrooms small pupils, wet mouth, sweating, wet eyes, vomiting, slow pulse, diarrhoea, fits, unconsciousness
Opiates small pupils, slow breathing, unconsciousness, low temperature, sbw, weak pulse, vomiting
Amfetamines, cocaine, theophylline l arge pupils, fever, fast pulse, hallucinations, fits, anxiety, sweating, flushed skin, over- activity, confusion
Barbiturates, diazepam and similar drugs, meprobamate unconsciousness, low blood pressure, shallow breathing, low temperature

Drug withdrawal (a sudden stop in taking ethanol (alcohol), barbiturates, diazepam and similar medicines, opiates)

diarrhoea, gooseflesh, fast pulse, watering eyes, yawning, cramps, hallucinations, restlessness, shaking

 

 
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